Genetic programs constructed from layered logic gates in single cells TS Moon, C Lou, A Tamsir, BC Stanton, CA Voigt Nature 491 (7423), 249-253, 2012 | 693 | 2012 |
Ribozyme-based insulator parts buffer synthetic circuits from genetic context C Lou, B Stanton, YJ Chen, B Munsky, CA Voigt Nature biotechnology 30 (11), 1137-1142, 2012 | 431 | 2012 |
Cas9-Assisted Targeting of CHromosome segments CATCH enables one-step targeted cloning of large gene clusters W Jiang, X Zhao, T Gabrieli, C Lou, Y Ebenstein, TF Zhu Nature communications 6 (1), 8101, 2015 | 295 | 2015 |
Exploiting a precise design of universal synthetic modular regulatory elements to unlock the microbial natural products in Streptomyces C Bai, Y Zhang, X Zhao, Y Hu, S Xiang, J Miao, C Lou, L Zhang Proceedings of the National Academy of Sciences 112 (39), 12181-12186, 2015 | 189 | 2015 |
Synthesizing a novel genetic sequential logic circuit: a push‐on push‐off switch C Lou, X Liu, M Ni, Y Huang, Q Huang, L Huang, L Jiang, D Lu, M Wang, ... Molecular systems biology 6 (1), 350, 2010 | 168 | 2010 |
Paired design of dCas9 as a systematic platform for the detection of featured nucleic acid sequences in pathogenic strains Y Zhang, L Qian, W Wei, Y Wang, B Wang, P Lin, W Liu, L Xu, X Li, D Liu, ... ACS Synthetic Biology 6 (2), 211-216, 2017 | 158 | 2017 |
Insulated transcriptional elements enable precise design of genetic circuits Y Zong, HM Zhang, C Lyu, X Ji, J Hou, X Guo, Q Ouyang, C Lou Nature communications 8 (1), 52, 2017 | 97 | 2017 |
Ribosome binding site libraries and pathway modules for shikimic acid synthesis with Corynebacterium glutamicum B Zhang, N Zhou, YM Liu, C Liu, CB Lou, CY Jiang, SJ Liu Microbial cell factories 14, 1-14, 2015 | 89 | 2015 |
Intermediate-sensor assisted push–pull strategy and its application in heterologous deoxyviolacein production in Escherichia coli M Fang, T Wang, C Zhang, J Bai, X Zheng, X Zhao, C Lou, XH Xing Metabolic engineering 33, 41-51, 2016 | 79 | 2016 |
De novo design of an intercellular signaling toolbox for multi-channel cell–cell communication and biological computation P Du, H Zhao, H Zhang, R Wang, J Huang, Y Tian, X Luo, X Luo, M Wang, ... Nature communications 11 (1), 4226, 2020 | 75 | 2020 |
Semirational Approach for Ultrahigh Poly(3-hydroxybutyrate) Accumulation in Escherichia coli by Combining One-Step Library Construction and High-Throughput … T Li, J Ye, R Shen, Y Zong, X Zhao, C Lou, GQ Chen ACS Synthetic Biology 5 (11), 1308-1317, 2016 | 69 | 2016 |
Orthogonality and Burdens of Heterologous AND Gate Gene Circuits in E. coli Q Liu, J Schumacher, X Wan, C Lou, B Wang ACS synthetic biology 7 (2), 553-564, 2018 | 67 | 2018 |
An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters T Hao, Z Xie, M Wang, L Liu, Y Zhang, W Wang, Z Zhang, X Zhao, P Li, ... Nature Communications 10 (1), 3665, 2019 | 57 | 2019 |
A molecular model for persister in E. coli C Lou, Z Li, Q Ouyang Journal of theoretical biology 255 (2), 205-209, 2008 | 55 | 2008 |
Engineering of core promoter regions enables the construction of constitutive and inducible promoters in Halomonas sp. T Li, T Li, W Ji, Q Wang, H Zhang, GQ Chen, C Lou, Q Ouyang Biotechnology Journal 11 (2), 219-227, 2016 | 48 | 2016 |
d-Sedoheptulose-7-phosphate is a common precursor for the heptoses of septacidin and hygromycin B W Tang, Z Guo, Z Cao, M Wang, P Li, X Meng, X Zhao, Z Xie, W Wang, ... Proceedings of the National Academy of Sciences 115 (11), 2818-2823, 2018 | 45 | 2018 |
A tight cold-inducible switch built by coupling thermosensitive transcriptional and proteolytic regulatory parts Y Zheng, F Meng, Z Zhu, W Wei, Z Sun, J Chen, B Yu, C Lou, GQ Chen Nucleic Acids Research 47 (21), e137-e137, 2019 | 39 | 2019 |
Systematically investigating the key features of the DNase deactivated Cpf1 for tunable transcription regulation in prokaryotic cells C Miao, H Zhao, L Qian, C Lou Synthetic and Systems Biotechnology 4 (1), 1-9, 2019 | 38 | 2019 |
A novel approach for metabolic pathway optimization: Oligo-linker mediated assembly (OLMA) method S Zhang, X Zhao, Y Tao, C Lou Journal of biological engineering 9, 1-10, 2015 | 30 | 2015 |
Rational design of an ultrasensitive quorum-sensing switch W Zeng, P Du, Q Lou, L Wu, HM Zhang, C Lou, H Wang, Q Ouyang ACS synthetic biology 6 (8), 1445-1452, 2017 | 25 | 2017 |