Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi E Choy, VK Chiu, J Silletti, M Feoktistov, T Morimoto, D Michaelson, ... Cell 98 (1), 69-80, 1999 | 980 | 1999 |
Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding D Michaelson, J Silletti, G Murphy, P D'Eustachio, M Rush, MR Philips The Journal of cell biology 152 (1), 111-126, 2001 | 882 | 2001 |
Ras signalling on the endoplasmic reticulum and the Golgi VK Chiu, T Bivona, A Hach, JB Sajous, J Silletti, H Wiener, RL Johnson, ... Nature cell biology 4 (5), 343-350, 2002 | 791 | 2002 |
Regulating the regulator: post-translational modification of RAS IM Ahearn, K Haigis, D Bar-Sagi, MR Philips Nature reviews Molecular cell biology 13 (1), 39-51, 2012 | 664 | 2012 |
Shp2 regulates SRC family kinase activity and Ras/Erk activation by controlling Csk recruitment SQ Zhang, W Yang, MI Kontaridis, TG Bivona, G Wen, T Araki, J Luo, ... Molecular cell 13 (3), 341-355, 2004 | 549 | 2004 |
PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis TG Bivona, SE Quatela, BO Bodemann, IM Ahearn, MJ Soskis, A Mor, ... Molecular cell 21 (4), 481-493, 2006 | 544 | 2006 |
Phospholipase Cγ activates Ras on the Golgi apparatus by means of RasGRP1 TG Bivona, I Pérez de Castro, IM Ahearn, TM Grana, VK Chiu, PJ Lockyer, ... Nature 424 (6949), 694-698, 2003 | 532 | 2003 |
Compartmentalized ras/mapk signaling A Mor, MR Philips Annu. Rev. Immunol. 24, 771-800, 2006 | 530 | 2006 |
Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors. BN Cronstein, RI Levin, M Philips, R Hirschhorn, SB Abramson, ... Journal of immunology (Baltimore, Md.: 1950) 148 (7), 2201-2206, 1992 | 472 | 1992 |
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum Q Dai, E Choy, V Chiu, J Romano, SR Slivka, SA Steitz, S Michaelis, ... Journal of Biological Chemistry 273 (24), 15030-15034, 1998 | 437 | 1998 |
Thematic review series: Lipid Posttranslational Modifications CAAX modification and membrane targeting of Ras LP Wright, MR Philips Journal of lipid research 47 (5), 883-891, 2006 | 427 | 2006 |
Targeting RAS membrane association: back to the future for anti-RAS drug discovery? AD Cox, CJ Der, MR Philips Clinical Cancer Research 21 (8), 1819-1827, 2015 | 390 | 2015 |
Receptor activation alters inner surface potential during phagocytosis T Yeung, M Terebiznik, L Yu, J Silvius, WM Abidi, M Philips, T Levine, ... Science 313 (5785), 347-351, 2006 | 384 | 2006 |
Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway JS Goodwin, KR Drake, C Rogers, L Wright, J Lippincott-Schwartz, ... The Journal of cell biology 170 (2), 261-272, 2005 | 349 | 2005 |
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion AY Chan, SJ Coniglio, Y Chuang, D Michaelson, UG Knaus, MR Philips, ... Oncogene 24 (53), 7821-7829, 2005 | 311 | 2005 |
Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils MR Philips, MH Pillinger, R Staud, C Volker, MG Rosenfeld, ... Science 259 (5097), 977-980, 1993 | 264 | 1993 |
Single-walled carbon nanotubes deliver peptide antigen into dendritic cells and enhance IgG responses to tumor-associated antigens CH Villa, T Dao, I Ahearn, N Fehrenbacher, E Casey, DA Rey, ... ACS nano 5 (7), 5300-5311, 2011 | 253 | 2011 |
Membranes as messengers in T cell adhesion signaling ML Dustin, TG Bivona, MR Philips Nature immunology 5 (4), 363-372, 2004 | 252 | 2004 |
Modes of action of aspirin-like drugs: salicylates inhibit erk activation and integrin-dependent neutrophil adhesion MH Pillinger, C Capodici, P Rosenthal, N Kheterpal, S Hanft, MR Philips, ... Proceedings of the National Academy of Sciences 95 (24), 14540-14545, 1998 | 228 | 1998 |
K-Ras4A splice variant is widely expressed in cancer and uses a hybrid membrane-targeting motif FD Tsai, MS Lopes, M Zhou, H Court, O Ponce, JJ Fiordalisi, JJ Gierut, ... Proceedings of the National Academy of Sciences 112 (3), 779-784, 2015 | 217 | 2015 |