The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells AP Bracken, D Kleine-Kohlbrecher, N Dietrich, D Pasini, G Gargiulo, ... Genes & development 21 (5), 525-530, 2007 | 1028 | 2007 |
Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer R Di Micco, G Sulli, M Dobreva, M Liontos, OA Botrugno, G Gargiulo, ... Nature cell biology 13 (3), 292-302, 2011 | 385 | 2011 |
In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural-and malignant glioma-stem cell homeostasis G Gargiulo, M Cesaroni, M Serresi, N de Vries, D Hulsman, ... Cancer cell 23 (5), 660-676, 2013 | 204 | 2013 |
SOX2 is the determining oncogenic switch in promoting lung squamous cell carcinoma from different cells of origin G Ferone, JY Song, KD Sutherland, R Bhaskaran, K Monkhorst, ... Cancer cell 30 (4), 519-532, 2016 | 203 | 2016 |
Polycomb repressive complex 2 is a barrier to KRAS-driven inflammation and epithelial-mesenchymal transition in non-small-cell lung cancer M Serresi, G Gargiulo, N Proost, B Siteur, M Cesaroni, M Koppens, H Xie, ... Cancer cell 29 (1), 17-31, 2016 | 125 | 2016 |
The chromodomain helicase Chd4 is required for Polycomb‐mediated inhibition of astroglial differentiation A Sparmann, Y Xie, E Verhoeven, M Vermeulen, C Lancini, G Gargiulo, ... The EMBO journal 32 (11), 1598-1612, 2013 | 102 | 2013 |
Deletion of polycomb repressive complex 2 from mouse intestine causes loss of stem cells MAJ Koppens, G Bounova, G Gargiulo, E Tanger, H Janssen, ... Gastroenterology 151 (4), 684-697. e12, 2016 | 82 | 2016 |
Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells C Lancini, PCM van den Berk, JHA Vissers, G Gargiulo, JY Song, ... Journal of Experimental Medicine 211 (9), 1759-1777, 2014 | 81 | 2014 |
Targeting APLN/APLNR improves antiangiogenic efficiency and blunts proinvasive side effects of VEGFA/VEGFR2 blockade in glioblastoma G Mastrella, M Hou, M Li, VM Stoecklein, N Zdouc, MNM Volmar, H Miletic, ... Cancer research 79 (9), 2298-2313, 2019 | 78 | 2019 |
NA-Seq: a discovery tool for the analysis of chromatin structure and dynamics during differentiation G Gargiulo, S Levy, G Bucci, M Romanenghi, L Fornasari, KY Beeson, ... Developmental cell 16 (3), 466-481, 2009 | 61 | 2009 |
NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1 C Marques, T Unterkircher, P Kroon, B Oldrini, A Izzo, Y Dramaretska, ... Elife 10, e64846, 2021 | 58 | 2021 |
Epigenomic profiling of cancer cells G Gargiulo, S Minucci The International Journal of Biochemistry & Cell Biology 41 (1), 127-135, 2009 | 56 | 2009 |
Phenotypic mapping of pathologic cross-talk between glioblastoma and innate immune cells by synthetic genetic tracing MJ Schmitt, C Company, Y Dramaretska, I Barozzi, A Göhrig, S Kertalli, ... Cancer discovery 11 (3), 754-777, 2021 | 54 | 2021 |
Next-Generation in vivo Modeling of Human Cancers G Gargiulo Frontiers in Oncology 8, 429, 2018 | 52 | 2018 |
Functional antagonism of chromatin modulators regulates epithelial-mesenchymal transition M Serresi, S Kertalli, L Li, MJ Schmitt, Y Dramaretska, J Wierikx, ... Science advances 7 (9), eabd7974, 2021 | 45 | 2021 |
In vivo shRNA screens in solid tumors G Gargiulo, M Serresi, M Cesaroni, D Hulsman, M Van Lohuizen Nature protocols 9 (12), 2880-2902, 2014 | 41 | 2014 |
Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities M Serresi, B Siteur, D Hulsman, C Company, MJ Schmitt, C Lieftink, ... Journal of Experimental Medicine 215 (12), 3115-3135, 2018 | 40 | 2018 |
HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness JSY Ho, F Di Tullio, M Schwarz, D Low, D Incarnato, F Gay, T Tabaglio, ... Elife 10, e59654, 2021 | 32 | 2021 |
Cannabidiol converts NF-κB into a tumor suppressor in glioblastoma with defined antioxidative properties MNM Volmar, J Cheng, H Alenezi, S Richter, A Haug, Z Hassan, ... Neuro-oncology 23 (11), 1898-1910, 2021 | 30 | 2021 |
USP15 deubiquitinase safeguards hematopoiesis and genome integrity in hematopoietic stem cells and leukemia cells P van den Berk, C Lancini, M Serresi, MP Sanchez-Bailon, D Hulsman, ... Cell Reports 33 (13), 2020 | 14 | 2020 |